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Article: Interactions between Inhibitory Interneurons and Excitatory Associational Circuitry in Determining Spatio-Temporal Dynamics of Hippocampal Dentate Granule Cells: A Large-Scale Computational Study.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Hendrickson PJ; Yu GJ; Song D; Berger TW
Front Syst Neurosci, 2015


Synaptic parameters, including numbers of synapses, synaptic weights, EPSP/IPSP magnitudes and rise/fall times, and reversal potentials.

Synapse counts:
GC # spines – inner 1/3 1150–1350 GC to BC 500–1400
GC # spines – middle 1/3 1050–1200 MEC to BC 100–200
GC # spines – outer 1/3 1100–1300 LEC to BC 100–200
BC to GC 40–80
MC to GC 750–850 MC to BC 950–1050
Synaptic weights:
MEC to GC 1.17E-5 GC to BC 1.13E-4
LEC to GC 1.50E-5 MEC to BC 4.21E-6
BC to GC 1.09E-5 LEC to BC 4.21E-6
GC to MC 2.00E-5 MC to GC 1.17E-6
MC to BC 2.27E-5
EPSP/IPSP rise time (ms):
MEC to GC 1.05 GC to BC 0.1
LEC to GC 1.05 EC to BC 1.05
BC to GC 1.05
EPSP/IPSP fall time (ms):
MEC to GC 5.75 GC to BC 0.59
LEC to GC 5.75 EC to BC 18
BC to GC 5.75
Reversal potentials (mV):
MEC to GC 0 GC to BC 0
LEC to GC 0 EC to BC 0
BC to GC -75

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source